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Research Nut: Mixed Nuts

Association of nut consumption and sarcopenia in Chinese older adults.

Xu, J., K. Pu, W. Sun, C. Pang, D. Li, S. Zang, 2025. Association of nut consumption and sarcopenia in Chinese older adults. Sci Rep. 15, 17598. https://doi.org/10.1038/s41598-025-02389-x

Sarcopenia emerges as a predominant health concern among the older adults, it makes the identification of relational factors crucial. Nut, a universally consumed dietary component, is posited to confer benefits to the musculoskeletal system. This study aimed to elucidate the association between nut consumption and sarcopenia in Chinese older adults. Data concerning nut consumption and sarcopenia were sourced from the 2018 wave of the Chinese Longitudinal Healthy Longevity Survey (CLHLS). The analysis incorporated 14,281 participants furnishing valid responses. This research employed logistic regression to investigate the association between nut consumption and sarcopenia. A total of 14,181 older adults (mean age = 84.86 ± 11.47 years and 55.08% were female) were included in this study. This study found an inverse association between nut consumption and sarcopenia in Chinese older adults, with higher nut consumption associated with a lower prevalence of sarcopenia, even after controlling for confounders. Compared with the nut consumption group of occasionally/rarely or never, the adjusted ORs of sarcopenia for at least once per month, at least once per week, and almost every day were 0.78 (95% CI: 0.66, 0.91), 0.81 (95% CI: 0.69, 0.95), and 0.62 (95% CI: 0.51, 0.77), respectively. Moreover, the result also displayed there is a significant interaction of nut consumption with gender (P-value = 0.016). This study identified an inverse association between nut consumption and sarcopenia. Introducing nut into the dietary regimen might present an accessible approach to bolster musculoskeletal health among the older adults.

Basophil activation test for the improved diagnosis of peanut and tree nut allergy.

Marini-Rapoport, O., M. Bhowmik, S.U. Patil, 2025. Basophil activation test for the improved diagnosis of peanut and tree nut allergy. Curr Allergy Asthma Rep 25, 19. https://doi.org/10.1007/s11882-025-01200-1

Purpose of review: As an ex-vivo test of allergic effector cell activation, basophil activation testing (BAT) to allergen enables quantification of the in-vivo IgE-mediated allergic response. BAT thus holds promise in the diagnosis and monitoring of peanut and tree nut allergies. Recent systematic analyses and expert recommendations support a role for BAT in the diagnosis of peanut and tree nut allergy. Recent findings: Diagnostic cut-offs for BAT in peanut and tree nut allergy have been identified. Consistently, BAT can discriminate with high sensitivity and specificity between allergy and tolerance when measured against oral food challenges. Furthermore, the utilization of BAT has can increase the sensitivity and specificity of peanut allergy and tree nut allergy diagnosis, both alone and in conjunction with specific IgE testing and skin prick testing. Summary: BAT is a promising tool in the diagnosis of peanut and tree nut allergy.

Upcycling commercial nut byproducts for food, nutraceutical, and pharmaceutical applications: A comprehensive review.

Alasalvar, C., G. Huang, B.W. Bolling, P.A. Jantip, R.B. Pegg, X.K. Wong, S.K. Chang, E. Pelvan, A.C. de Camargo, G. Mandalari, A. Hossain, F. Shahidi, 2025. Upcycling commercial nut byproducts for food, nutraceutical, and pharmaceutical applications: A comprehensive review. Food Chem. 467:142222. https://doi.org/10.1016/j.foodchem.2024.142222

This article presents a comprehensive overview of upcycling commercial nut byproducts (such as almond, Brazil nut, cashew, hazelnut, macadamia, peanut (also known as a legume), pecan, pine nut, pistachio, and walnut) for food, nutraceutical, and pharmaceutical applications. Upcycling nut byproducts, namely husk/hull, hard shell, brown skin, defatted flour/meal/cake, pine cone, cashew nut shell liquid, cashew apple, walnut septum, and dreg/okara, has great potential, not only to reduce/minimise waste, but also to fit within the circular economy concept. Each byproduct has its own unique functional properties, which can bring significant value. These byproducts can be used as value-added ingredients to promote better health and well-being, due to their rich sources of diverse bioactive components/phytochemicals, polysaccharides, fibre, lignin, prebiotics, oils, proteins, bioactive peptides, minerals, and vitamins, among other components. This comprehensive review provides a basis for future research and development of product applications for nut byproducts. More studies are needed on novel product development to valorise nut byproducts.

Nut consumption is associated with cognitive status in Southern Italian adults. 

Godos, J., F. Giampieri, E. Frias-Toral, R. Zambrano-Villacres, A.O.R. Vistorte, V. Yélamos Torres, M. Battino, F. Galvano, S. Castellano, G. Grosso, 2025. Nut consumption is associated with cognitive status in Southern Italian adults. Nutrients. 17(3), 521.  DOI: 10.3390/nu17030521, https://www.mdpi.com/2072-6643/17/3/521

Background: Nut consumption has been considered a potential protective factor against cognitive decline. The aim of this study was to test whether higher total and specific nut intake was associated with better cognitive status in a sample of older Italian adults. Methods: A cross-sectional analysis on 883 older adults (>50 y) was conducted. A 110-item food frequency questionnaire was used to collect information on the consumption of various types of nuts. The Short Portable Mental Status Questionnaire was used to assess cognitive status. Multivariate logistic regression analyses were performed to calculate odds ratios (ORs) and 95% confidence intervals (CIs) for the association between nut intake and cognitive status after adjusting for potential confounding factors. Results: The median intake of total nuts was 11.7 g/day and served as a cut-off to categorize low and high consumers(meanintake4.3g/day vs. 39.7g/day, respectively). Higher total nut intake was significantly associated with a lower prevalence of impaired cognitive status among older individuals (OR = 0.35, CI 95%: 0.15, 0.84) after adjusting for potential confounding factors. Notably, this association remained significant after additional adjustment for adherence to the Mediterranean dietary pattern as an indicator of diet quality, (OR = 0.32, CI 95%: 0.13, 0.77). No significant associations were found between cognitive status and specific types of nuts. Conclusions: Habitual nut intake is associated with better cognitive status in older adults