Part 1: Immunopathogenesis and clinical disorders.

• Date posted:  01/21/1999 
• Posted In:
• Mixed Nuts,
• Nut Allergy,

Sampson, H.A., 1999. Food allergy. Part 1: Immunopathogenesis and clinical disorders. J Allergy Clin Immunol. 103:717-728.

Up to 8% of children less than 3 years of age and approximately 2% of the adult population experience food-induced allergic disorders. A limited number of foods are responsible for the vast majority of food-induced allergic reactions: milk, egg, peanuts, fish, and tree nuts in children and peanuts, tree nuts, fish, and shellfish in adults. Food-induced allergic reactions are responsible for a variety of symptoms involving the skin, gastrointestinal tract, and respiratory tract and may be caused by IgE-mediated and non-IgE-mediated mechanisms. In part 1 of this series, immunopathogenic mechanisms and clinical disorders of food allergy are described.